Robin Williams Hunter 'Patch' Adams

Monica Potter Carin Fisher

Philip Seymour Hoffman Mitch Roman

Daniel London Truman Schiff

Bob Gunton Dean Walcott

Harve Presnell Dean Anderson

Peter Coyote Bill Davis

Michael Jeter Rudy

Josef Sommer Dr. Eaton

Irma P. Hall Joletta

Barry Shabaka Henley Emmet

Frances Lee McCain Judy

Daniella Kuhn Adelane

James Greene Bile

Harold Gould Arthur Mendelson

Bruce Bohne Trevor Beene

Harry Groener Dr. Prack

Steven Anthony Jones Charlie

Richard Kiley Dr. Titan

Douglas Roberts Larry

Ellen Albertini Dow Aggie

Alan Tudyk Everton

Ryan Hurst Neil

Peter Siteri Chess Man

Don West Instructor

Greg Sestero Jaime

Jason Aaron Baca Patch Pirate

Ismael 'East' Carlo Hispanic Father

Diane Amos Older Waitress

Andy Arness Orderly (uncredited)

Renee Rogers Receptionist

Dot-Marie Jones Miss Meat

Ralph Peduto Organizer

Norman Alden Truck Driver

Sonya Eddy Older Waitress